Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

Shiwen Song, Mingyang Zhao, Xiangrong Song, Huaidong Yu, Xin Xu, Dong Sun, Jingkai Gu

PDF(3370 KB)

　

Search
Submit
E-mail
RSS

Chinese Chemical Letters ›› 2026, Vol. 37 ›› Issue (02) : 112099. DOI: 10.1016/j.cclet.2025.112099

Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

{{article.zuoZhe_EN}}

Author information +

History +

HeighLight

{{article.keyPoints_en}}

Abstract

{{article.zhaiyao_en}}

Key words

Cite this article

Download Citations

{{article.zuoZheEn_L}}. {{article.title_en}}. {{journal.qiKanMingCheng_EN}}. 2026, 37(02): 112099 https://doi.org/10.1016/j.cclet.2025.112099

References

Publishing order | Descend order by publishing year | Descend order by cited within

References

{{article.reference}}

Funding

RIGHTS & PERMISSIONS

{{article.copyrightStatement_en}}

{{article.copyrightLicense_en}}

PDF(3370 KB)

Accesses

Citation

Detail

Sections

Recommended

/

〈

〉