Efficient continuous synthesis of 2-[3-(trifluoromethyl)phenyl]malonic acid, a key intermediate of Triflumezopyrim, coupling with esterification-condensation-hydrolysis

Efficient continuous synthesis of 2-[3-(trifluoromethyl)phenyl]malonic acid, a key intermediate of Triflumezopyrim, coupling with esterification-condensation-hydrolysis

Yuexiang Liu, Xiangqiao Yang, Tong Lin, Guantian Yang, Xiaoyong Xu, Bubing Zeng, Zhong Li, Weiping Zhu, Xuhong Qian

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Chinese Chemical Letters ›› 2025, Vol. 36 ›› Issue (01) : 109747. DOI: 10.1016/j.cclet.2024.109747

Efficient continuous synthesis of 2-[3-(trifluoromethyl)phenyl]malonic acid, a key intermediate of Triflumezopyrim, coupling with esterification-condensation-hydrolysis

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{{article.zuoZheEn_L}}. {{article.title_en}}. {{journal.qiKanMingCheng_EN}}. 2025, 36(01): 109747 https://doi.org/10.1016/j.cclet.2024.109747

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