中国化学快报

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Selective De-O-acetylation in TCP-containing Carbohydrate Structures with Magnesium Methoxide

Zhi Hui QIN, Hui LI, Meng Shen CAI, Zhong Jun LI

中国化学快报. 2000, 11(11): 941-942.

摘要 ( )

可视化

Magnesium methoxide can be used for TCP-containing substrates to remove acetyl group successfully while leaving the TCP-group virtually intact.

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Selective De-O-acetylation in TCP-containing Carbohydrate with Magnesium Methoxide

中国化学快报. 2000, 11(11): 943-944.

摘要 ( )

可视化

The crude product was purified by column chromatography, eluting with 25:1 CHCl₃/MeOH to afford the title compound in 75% yield. Rf:0.32(CHCl₃/MeOH 20:1).

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Photoinitiated Reaction of β-Bromonaphthalene with Pinacolone Ion in DMSO

Zhao Bin CHEN, Li Yun ZHAO, Zhao ZHANG

中国化学快报. 2000, 11(11): 945-948.

摘要 ( )

可视化

The photoinitiated reaction of β-bromonaphthalene with excess pinacolone enolate does not yield expected normal S_RN 1 product 1-β-naphthyl-3,3-dimethyl-2-butanone, 3, but a more complex molecule 2,2-dimethyl-5-(1',1'-dimethylethyl)-6-β-naphthyl-5-hexene-3-one, 4, deriving from it. The reaction is inhibited by m-dinitrobenzene and do not occur in the absence of light. Structure analysis of the product, along with other evidence, indicates a mechanism for this reaction, where addition of a further pinacolone molecule to carbonyl group of 3 and subsequent elimination of a water molecule would afford product 4, once the S_RN1 substitution product 3 has formed.

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Abnormal Nucleophilic Reaction of Ethyl Crotonate:An Easy Way to Form Novel Imidazo[1,5-a] pyridine derivatives

Hong Mei LI, Cong WANG, Jian Wu WANG

中国化学快报. 2000, 11(11): 949-950.

摘要 ( )

可视化

An abnormal intramolecular nucleophilic reaction of αβ-carbon of α,β-unsaturated ester was discovered and the reaction makes it very easy to form imidazo[1,5-a]pyridine derivatives. The mechanism of the reaction was discussed.

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Site-specifically Hydrolytic Cleavage of Oxidized Insulin B Chain With Cu(Ⅱ) Ion

Xue Mei LUO, Wei Jiang HE, Yu ZHANG, Zi Jian GUO, Long Gen ZHU

中国化学快报. 2000, 11(11): 951-954.

摘要 ( )

可视化

Electrospray mass spectrometry investigation shows that denatured oxidized insulin B chain can be selectively cleaved by simple Cu(Ⅱ) ion and the site of cleavage is at Gly8-Ser9 bond which is second amide bond left from His 10 in the sequence of oxidized insulin B chain.

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Solid Phase Synthesis of β-Carbolines

Jing Xin ZHANG, Xiao Chuan TAN, Ping XIE, Xiao Tian LIANG

中国化学快报. 2000, 11(11): 955-956.

摘要 ( )

可视化

Synthesis of β-carbolines on solid phase using TCCA as the key reagent is developed.

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Asymmetric Synthesis of (3R, 5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-Bromovinyl)-Tetrahydro-Furan-2-one, an Intermediate for the Synthesis of Fostriecin

Su Yun LIU, Dao Fei HUANG, Hai Hong HUANG, Liang HUANG

中国化学快报. 2000, 11(11): 957-960.

摘要 ( )

可视化

(3R,5R)-3-((tert-Butyldimethylsily)oxy)-5-((Z)-2-bromovinyl)-tetrahydro-furan-2-one, an intermediate for the synthesis of Fostriecin was achieved by intramolecular asymmetric induction in propene addition of (-)-8-phenylmenthyl glyoxylate followed by inversion of C₃-hydroxyl group and Sharpless asymmetric dihydroxylation with simultaneous cyclization to give lactone 5. Then protection of C₃-hydroxyl group and oxidation of the C₆-primary hydroxyl group which reacted with Wittig reagent to yield the target compound4.

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Synthesis of Novel Isoxazole-contained Analogues of Losartan

Jian Wu WANG, Jiong JIA, Hong Mei LI, Cong WANG

中国化学快报. 2000, 11(11): 961-962.

摘要 ( )

可视化

A series of novel isoxazole-contained analogues of Losartan were designed and synthesized with 1,3-DC reaction. The regioselectivity of the reaction was discussed and the compounds are potential antihypertensive.

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Synthesis of demethoxy-amino-substituted hypocrellins:novel photosensitizers for photodynamic therapy

Tao WU, Shang Jie XU, Jian Quan SHEN, Shen CHEN, Man Hua ZHANG, Tao SHEN

中国化学快报. 2000, 11(11): 963-966.

摘要 ( )

可视化

A novel method was used to obtain demethoxy-amino-substituted hypocrellin derivatives. Peri-hydroxylated perylenequinone structure of hypocrellin was reserved when hypocrellin reacted with an amine in pyridine. The products were new compounds with significant cytotoxicity against tumor cells. Their structures have been established on the basis of their mass and ¹H NMR spectra.

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The Synthesis of 6-Alkyl-5-Fluorouracil Derivatives

Jin Zong YOU, Shao Yuan CHEN, Yao Zu CHEN

中国化学快报. 2000, 11(11): 967-970.

摘要 ( )

可视化

6-alkyl-5-fluorouracil derivatives (5a~5f) were synthesized by facile alkylation of lithiation of 5-fluorouracil derivatives with mthyl iodide (MeI) or alkyl trifluoromethanesulfonate (ROTf) in yield of 42~58%. We found that the methylated product was ethyl-substituted derivatives, not methyl-substituted derivatives.

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The Synthesis of a Novel Lignan

Xiu Xiang QI, Jun Biao CHANG, Rui Yun GUO, Rong Feng CHEN

中国化学快报. 2000, 11(11): 971-974.

摘要 ( )

可视化

A short convenient synthesis of a novel lignan, 2-(3',4',5'-trimethyoxyphenyl)-1,3-dimethyl-6,7,8-trimethoxy-naphthalene has been accomplished by the condensation of key intermediates, 3,4,5-trimethoxybenzyl methyl ketone with TiCl₄.

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Synthesis and Isolation of Diastereomers of Optically Active Cyclomercurated Ferrocenylimines

Yang Jie WU, Xiu Ling CUI, Mao Ping SONG, Ning ZHOU, Chen Xia DU, Yu ZHU

中国化学快报. 2000, 11(11): 975-978.

摘要 ( )

可视化

Asymmetric cyclomercuration of chiral ferrocenylimines (+)-(R)-2 and (-)-(S)-2 with mercuric acetate and subsequent treatment by lithium chloride gave a mixture of diastereomeric cyclomercurated ferrocenylimines. The four enantiomeric pure compounds with both planar and central chirality were isolated from the two mixtures by the thin layer chromatography.

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Synthesis and Catalyzing Behavior of Olefin Polymerization of cis-Cyclopentene Bridged Titanocenes

Jin Shan LI, Chuan Hui XIONG, Yong Qiang MA, Jing LI, Xu CHEN

中国化学快报. 2000, 11(11): 979-980.

摘要 ( )

可视化

Two cis-cyclopentene bridged titanocenes have been synthesized. Two homogeneous Ziegler catalysts prepared by activation of synthesized compounds with methylalumoxane are active for ethylene polymerization reactions.

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Conformation Analysis and Thermodynamics of Binding Behavior of DABCO to p/p type Dimeric Porphyrin Hosts

Qi Zhi REN, Zhi Ang ZHU, Jin Wang HUANG, Liang Nian JI, Yong Ti CHEN

中国化学快报. 2000, 11(11): 981-984.

摘要 ( )

可视化

The binding conformations of bidentate ligand DABCO(1,4-diazobicyclo[2,2,2]octane) to a series of p/p type zinc porphyrin dimers covalently linked with flexible alkoxy chain-O(CH₂)_n O- (n=2~10) are described by ₁H NMR and UV-vis spectroscopy. DABCO can bind inside the cavities of porphyrin dimers and form a ternary sandwich complex as the alkoxy chain length is long enough. The thermodynamic parameters which control the binding behavior are investigated.

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A Molecular Modeling for the Complexation of Cyclobis(paraquat-p-phenylene) with Substituted Benzenes and Biphenyls

Ke Chun ZHANG, Lei LIU, Ting Wei MU, Qing Xiang GUO

中国化学快报. 2000, 11(11): 985-988.

摘要 ( )

可视化

Molecular orbital PM3 calculation was performed on the complexation of cyclobis(para-quat-p-phenylene) with a number of 1,4-disubstituted benzenes and biphenyl derivatives. A fair correlation was found between the PM3 calculated binding energies and the experimental ones, which enabled the PM3 calculation to predict the experimental binding energies for a number of important complexes. A good structure-activity relationship was also found between the PM3 calculated binding energies and the substituent molar refraction R_m and Hammett ó constants, indicating that the van der Waals force and the electronic interactions constituted the major driving forces for the complexation of cyclobis(paraquat-p-phenylene).

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A New Perturbed Hard-Sphere Equation of State

Shou Gang WANG, Hong Wei XIANG, Bu Xing HAN

中国化学快报. 2000, 11(11): 989-992.

摘要 ( )

可视化

A new equation of state based on hard-sphere perturbed theory was developed. This equation combined the CS repulsive term and Guo-Du attractive term. Parameters of 38 substances were estimated, the pressure-volume-temperature properties were calculated and compared with two other equations. The results show that this equation is more accurate.

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A New Compound from Dalbergia odorifera T. Chen

Wen WANG, Qi Xiu ZHU, Ming Hua HUANG, Dong Liang CHENG

中国化学快报. 2000, 11(11): 993-994.

摘要 ( )

可视化

A new compound, 2, 4-dihydroxy-5-methoxybenzophenone was isolated from the root and heartwood of Dalbergia odorifera T. Chen.

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Two New ent-Kaurane Diterpenoids from Isodon adenantha

Bei JIANG, Ji Chun XU, Hui YANG, Qin Shi ZHAO, Han Dong SUN

中国化学快报. 2000, 11(11): 995-996.

摘要 ( )

可视化

Two new ent-kaurane diterpenoids, adenanthins B (1) and C (2), were isolated from the EtOAc extract of Isodon adenantha. Their structures were elucidated by spectroscopic evidences.

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Depsides from Prunella vulgaris

Zhu Ju WANG, Yu Ying ZHAO, Bin WANG, Tie Min AI, Ya Yan CHEN

中国化学快报. 2000, 11(11): 997-1000.

摘要 ( )

可视化

A novel depsides 1, together with three known ones 2~4 and two phenylpropanoids 5~6 were isolated from the ethanol extract of the spikes of Prunella vulgaris. On the basis of spectral and chemical evidence, their structures were deternined as butyl rosmarinate 1, ethyl rosmarinate 2, methyl rosmarinate 3, rosmarinic acid 4, 3,4,α-trihydroxy-methyl phenylpropionate 5 and p-coumaric acid 6, respectively.

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Two New Phenolic Glycosides from Magnolia rostrata

Shi Ming DENG, Jun ZHOU, Yong Xian CHENG, Hao Fu DAI, Ning Hua TAN

中国化学快报. 2000, 11(11): 1001-1002.

摘要 ( )

可视化

Two new phenolic glycosides, 3, 4-dihydroxy-allylbenzene-3-O-α-L-rhamnopyranosyl (1→6)β-D-glucopyranoside (1) and 3, 4-dihydroxy-allylbenzene-3-O-α-L-rhamnopyranosyl (1→2) β-D-glucopyranoside (2), were isolated from the barks of Magnolia rostrata. Their structures were elucidated by spectroscopic and chemical methods, specially 2D NMR techniques.

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Structure of 6-Epiforsticine and Revision of the Stereochemistry of Forsticine

Feng Peng WANG, Zheng Bang LI, Ji Jun CHEN, Jin Song YANG

中国化学快报. 2000, 11(11): 1003-1004.

摘要 ( )

可视化

A norditerpenoid alkaloid, 6-epiforsticine, has been isolated from the roots of the plants Aconitum hemsleyanum var. pengzhouense and A. kuzsnezoffii and its structure has been established as 1 on the basis of 2D-NMR and X-ray diffraction analysis. The structure of forsticine has accordingly been revised from 1 to 2.

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Diterpenoid Alkaloids from Aconitum Nagarum var. Lasiandrum

Jin Yan Dong, Zi Yan Li, Liang Li

中国化学快报. 2000, 11(11): 1005-1006.

摘要 ( )

可视化

Two new diterpenoids, nagadine 1 and 14-benzoylsachaconitine 2 were isolated from the roots of Aconitum nagarum. Their structures were elucidated as 1 and 2 on the basis of spectral analysis.

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A New Sesquiterpene Lactones Glucoside from Notoseris psilolepis

Xiao Xia YE, Ji Shuang CHEN, Ming Kui WANG, Ke Xin HUANG, Li Sheng DING

中国化学快报. 2000, 11(11): 1007-1008.

摘要 ( )

可视化

A new sesquiterpene lactone glucoside, notoserolide C (1), was isolated from the whole plant of Notoseris psilolepis Shih. By means of spectral analysis including MS, NMR (¹HNMR, ¹³C NMR,¹H-¹H COSY, HMQC, HMBC) and X-ray diffraction, the structure of notoserolide C was established as cichorioside B angelate.

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New Sesquiterpenoids from Hedychium yunnanense gagnep

Xiu Hua LIU, Dong Bao ZHAO, Chong Ren YANG, Han Qing WANG

中国化学快报. 2000, 11(11): 1009-1012.

摘要 ( )

可视化

Two new sesquiterpenoid trialcohol isomers named 1β, 4α 11α-trihydroxyeudesmane (1) and Yunnanensehedychetriol (2), were isolated from the fresh rhizomes of Hedychium Yunnanense gagnep.Their structures were elucidated by spectroscopic methods.

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A New Triterpenoid Glycoside from Dichotomanthes tristaniaecarpa

Wen Li MEI, Xiao Dong LUO, Chang Xiang CHEN

中国化学快报. 2000, 11(11): 1013-1014.

摘要 ( )

可视化

A new triterpenoid glycoside 1, 1β, 2α, 3α, 19α-tetrahydroxyurs-12-en-28-oic acid β-D glucopyranosyl ester was isolated from Dichotomanthes tristaniaecarpa. The structure was elucidated on the basis of spectral means.

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A Novel Sieving Medium for Separation of DNA Fragments- Poly(acrylamide-dimethylacrylamide)

Ji Cun REN, Zheng Fa FANG

中国化学快报. 2000, 11(11): 1015-1018.

摘要 ( )

可视化

A short chain poly (acrylamide-dimethylacrylamide) was synthesized in water phase using isopropanol as a chain transfer agent. This copolymer can form a stable dynamic coating on the inner surface of the capillary, thereby suppressing the electroosmotic flow and DNA-capillary wall interaction. The high efficient separation of DNA fragments and SSCP analysis were obtained in bare capillaries using this copolymer as a sieving medium.

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A Gas Chromatographic Analysis of Light Hydrocarbons on a Column Packed with Modified Silica Gel

Xiao Zheng LAN, Dao Qian ZHU, Qing Hai WANG, Liang Mo ZHOU, Ya Feng GUAN

中国化学快报. 2000, 11(11): 1019-1022.

摘要 ( )

可视化

A one-meter long column packed with silica gel is used to separate light hydrocarbons. The silica gel has been modified with several kinds of gas chromatography stationary phases. Among these, PEG 2000 shows fairly good effect when using 80-100 meshes silica gel for the separation of mixture of methane, ethane, ethylene, acetylene, propane, propylene and n-, i-butane. The different behavior of silica gel between batch to batch is also found. When silica gel is coated with a small amount of Al₂O₃prepared with sol-gel method, better resolution has been observed on a 2-meter column compared with the non-modified silica gel.

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Preparation and Properties of Self-reinforced L-and D,L-lactide Copolymer Rods

Yu Shan HU, Zheng Pu ZHANG, Dong SONG, Yong Mei WANG, Dong Ren BAI

中国化学快报. 2000, 11(11): 1023-1026.

摘要 ( )

可视化

Since highly crystalline poly (L-lactide) (PLLA) degrades rather slowly in a biological environment and the crystalline domains remaining after partial degradation of the implant material give rise to an inflammatory response of the surrounding tissue, L- and D,L-lactide copolymer[P(L-DL)LA] having a low crystallinity is preferred in surgical applications. The thermal transitions and the mechanical properties of P(L-DL)LA rods were discussed in this paper. It was found that the self-reinforced P(L-DL)LA[SR-P(L-DL)LA] was strong enough in terms of mechanical properties compared with the self-reinforced PLLA[SR-PLLA].

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A New Strategy for Architecture of Robust Monolayer Based on Binuclear Palladium (Ⅱ) Complex of Calix[4]arene Derivative

Wei Jiang HE, Fang LIU, Zhi Feng YE, Zi Jian GUO, Jun Bai LI, Long Gen ZHU

中国化学快报. 2000, 11(11): 1027-1030.

摘要 ( )

可视化

A monolayer which is formed by a binuclear palladium complex of low rim methioninedisubstituted calix[4]arene exhibits extraordinary cohesiveness. Cohesiveness measurement and Brewster Angle Microscopy observation show that the monolayer is uniform and robust. This film is probably formed by self-assembly of precursor complex through strong chloride ion bridge between palladium centers.

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Production of Carbon Nanotubes over Pre-reduced LaCoO₃ Using Fluidized-bed Reactor

Bao Chun LIU, Qi LIANG, Shui Hua TANG, Li Zhen GAO, Bo Lan ZHANG, Mei Zhen QU, Zuo Long YU

中国化学快报. 2000, 11(11): 1031-1034.

摘要 ( )

可视化

Carbon nanotubes were synthesized on a large scale by the catalytic decomposition of hydrocarbons over pre-reduced LaCoO₃ using a fluidized-bed reactor. Reaction parameters such as reduction temperature, reduction time and reaction temperature were discussed.

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2000年, 第11卷, 第11期　刊出日期：2000-11-20

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2000年, 第11卷, 第11期 刊出日期：2000-11-20

2000年, 第11卷, 第11期　刊出日期：2000-11-20