1997年, 第8卷, 第12期　刊出日期：1997-12-20

  

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  Asymmetric Trimethylsilylcyanation of Benzaldebyde Catalyzed by Novel Ti(Ⅳ)-Chiral Schiff Base Complexes

  Guo Fu ZI, Cheng Lie YIN

  中国化学快报. 1997, 8(12): 1013-1014.

  摘要 ( ) 可视化 收藏

  Benzaldehyde has been trimethylsilylcyanated with a catalyst prepared in situ from titanium tetraisopropoxide and chiral Schiff bases.Cyanohydrin is obtained in moderate e.e.values.
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  Preparation of Chiral Quaternary Ammonium Salts and Initial Study of Asymmetric Phase Transfer Catalytic Alkylation

  Rong Liang LOU, Ai Qiao MI, Zhong Yuan ZHOU, Jun Mei ZHANG, Yao Zhong JIANG

  中国化学快报. 1997, 8(12): 1015-1016.

  摘要 ( ) 可视化 收藏

  A number of chiral quaternary ammonium salts were synthesized from (1R,2S)-(-)-1,2-diphenyl-2-aminoethanol and applied to the enantioselective alkylation.
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  Effect of Silyl Moiety on the Reaction of O,O'-Phenylenephosphoryl Chloride with N-Silylvaline Silyl Ester

  Qian WANG, Hai Yan LU, Yu Fen ZHAO

  中国化学快报. 1997, 8(12): 1017-1018.

  摘要 ( ) 可视化 收藏

  N-Trimethylsilylvaline trimethylsilyl ester Ⅱa,N-triethylsilylvaline triethylsilyl ester Ⅱb and N-tert-butyldimethylsilylvaline tert-butyldimethylester Ⅱc showed evidently different reactivities with O,O'-phenylenephosphorylchloride.The formation speed of the final spiro-bicyclic pentacoordinated phosphorus compounds Ⅳ depends on the intramolecular transfer ability of the silyl oiety crucially.
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  Asymmetric 1,3-Dipolar Cycloaddition of the Chiral Nitronic Esters with Acrylate

  Fu An KANG, Cheng Lie YIN

  中国化学快报. 1997, 8(12): 1019-1020.

  摘要 ( ) 可视化 收藏

  Asymmetric 1,3-dipolar cycloaddition of the chiral nitronic esters with acrylate giving the enantiomerically pure novel chiral bisheterocyclic compounds is described.
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  Synthesis of 3-Substituted-6-(2,4-Dichlorophenyl)-s-Triazolo[3.4-b]-1,3,4-Oxadiazoles

  Xiao Ming FENG, Xun HE, Yao Zhong JIANG

  中国化学快报. 1997, 8(12): 1021-1024.

  摘要 ( ) 可视化 收藏

  Fourteen new 2-acylhydrazino-5-(2,4-dichlorophenyl)-1,3,4-oxadiazoles were prepared by nucleophilic displacement of acylhydrazine at the 2-position of 2-methylsulfonyl-5-(2,4-dichlorophenyl)-1,3,4-oxadiazole.Fourteen new 3-substituted-6-(2,4-dichlorophenyl)-s-triazolo[3,4-b]-1,3,4-oxadiazoles were obtained by treating 2-acylhydrazino-5-(2,4-dichlorophenyl)-1,3,4-oxadiazoles with K₂CO₃ solution.All the new compounds showed significant antibacterial activity.
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  Synthesis of Macrocycles Containing Amino Acid Ester and Aryl-heterocyclic Units

  Yan Tao CHEN, Wen Ting HUA, Qi Yi XING

  中国化学快报. 1997, 8(12): 1025-1028.

  摘要 ( ) 可视化 收藏

  Four kinds of new macrocycles containing amino acids and aryl-heterocyclic units were synthesized by the condensation of di-esters containing Ts-amino acids units with di-halogenated compounds at room temperature.The macrocycles were characterized by elemental analysis,IR,MS(FAB) and ¹H NMR.
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  Synthesis of D-Fructofuranosides Using Phenyl Thioglycosides as Glycosyl Donors

  Jun XUE

  中国化学快报. 1997, 8(12): 1029-1030.

  摘要 ( ) 可视化 收藏

  Benzoylated phenyl α-and β-2-thio-D-fructofuranosides were synthesized and firstly used as donors in coupling with sucrose acceptor.α-Fructofuranoside was stereospecifically synthesized by employing NIS (N-iodosuccinimide)/AgOTf as catalysts.The structure of all products was confirmed by ¹³C-NMR or ¹H-NMR spectrum.
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  Sythesis of 4,5-Bisaryl-2-(2,5-Dimethylthiophen-3-yl) imidazoles and Their Dimers

  Jin Quan BAI, Xiao Chun HAN, Yong Mei WANG, Ji Ben MENG

  中国化学快报. 1997, 8(12): 1031-1032.

  摘要 ( ) 可视化 收藏

  4,5-diphenyl,4,5-bis(4-methylphenyl),4,5-bis(4-methoxyphenyl)-2-(2,5-dimethylthiophen-3-yl) imidazoles were synthesized.Oxidation of the obtained imidazoles with potassium ferricyanide in water-alcohol solution of alkali gave the corresponding dimers.The structures of imidazoles were characterized by IR,¹H NMR,mass spectroscopy and elemental analysis.The structures of dimers were characterized by IR,elemental analysis and chromatography.
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  Synthesis and Structure of 1,2-O-(1-Aryl-1-Propylidene)-D-Mannitol

  Jian Hua YU, Yu Lai HU, Wen Fei TAN, Shi Yan YANG, Yuan Qi YIN

  中国化学快报. 1997, 8(12): 1033-1036.

  摘要 ( ) 可视化 收藏

  A method for selective reaction of 1-aryl-propane-1-ones with 1,2-dihydroxy group of D-mannitol in the presence of ZnCl₂-BF₃.Et₂O to 1,2-O-(1-aryl-1-propylidene)-D-mannitol (1-4) is described.The compounds were first reported and determined by IR,MS,¹H-/¹³C-NMR spectra,among them the structure of 1 was further defined by X-ray diffraction.
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  Total Synthesis of Gnetifolin A

  Dao Fei HUANG, Xiang ZHANG, Shu Feng CHEN

  中国化学快报. 1997, 8(12): 1037-1040.

  摘要 ( ) 可视化 收藏

  Total synthesis of gnetifolin A was accomplished via intramolecular Wittig reaction.The synthesis started from 2-methoxy-3-methylhydroquinone and methyl 4-O-methylgallate through eight steps.
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  Study on the Total Synthesis of 3-Oxo-9β-Acetoxyilicic Acid-The Synthesis of 9β-Acetoxy-3(4),11(13)-Dien-5αH,7αH-12-Eudesmanoic Acid Methyl Ester

  Jiong YANG, Zhao Ming XIONG, Yong Gang CREN, Yu Lin LI

  中国化学快报. 1997, 8(12): 1041-1042.

  摘要 ( ) 可视化 收藏

  The synthesis of 9β-acetoxy-3(4),11(13)-dien-5αH,7αH-12-eudesmanoic acid methyl ester (2) was achieved from oxycarvone.The key step is the p-toluenesulfonhydrazide assisted reductive rearrangement reaction.
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  Studies on the Total Synthesis of Hainanolide (Ⅳ)-Revising the Stereochemistry of C_2a-H and Introducing the Two Hydroxy Groups at C_3β,C_4α Positions

  Wen Qian YANG, Xiao Ming YU, Shi Zhi CHEN, Liang HUANG

  中国化学快报. 1997, 8(12): 1043-1044.

  摘要 ( ) 可视化 收藏

  Tricyclic compound 6 was synthesized from compound 1 through six steps,thus problem of the stereochemistry of C_2a-H being solved.The stereochemistry for introducing hydroxy groups at C_3β and C_4α positions in compound 1 was also described.
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  Copolymerization of N-Phenylmaleimide with Cyclohexene

  Hua Ming LI, Hong Biao CHEN, Zhong Ming JIANG, Peng Sheng LIU

  中国化学快报. 1997, 8(12): 1045-1046.

  摘要 ( ) 可视化 收藏

  Radical copolymerization of N-phenylmaleimide with cyclohexene was carried out with 2,2-azobisisobutyronitrile in various solvents at 60℃.The copolymer was characterized by IR and ¹H-NMR.
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  Novel Phosphonoacetic Acid Derivatives. Synthesis of N-(Ethoxycarbonylmethylphosphonyl)-α-Amino Esters and-α-Amino Phosphonic Acid Esters and Their Bioactivities

  Hui Ying LI, Kang Tai REN, Ru Yu CHEN

  中国化学快报. 1997, 8(12): 1047-1050.

  摘要 ( ) 可视化 收藏

  A series of novel phosphonoacetic acid derivatives,N-(ethoxycarbonylmethyl-ethoxyphosphonyl)-α-amino acid esters and α-amino phosphonates,were synthesized via the reaction of the corresponding phosphonyl chloride with amino acid ester hydrochlorides or amino phosphonates in the presence of a base.The preliminary bioassay shows that some compounds show significant anti-viral activity against tobacco mosaic virus (TMV).
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  Reactivity of C-10 Function in Sinenxan A and Its Derivatives

  Fen Mei YAO, Dong Hui WANG, Guang Yan HUANG, Ji Yu GUO, Xiao Tian LIANG

  中国化学快报. 1997, 8(12): 1051-1054.

  摘要 ( ) 可视化 收藏

  The allylic nature of C-10 in sinenxan A (1) leads to facile S_N1 and elimination reactions.
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  A New Taxoid from Microbial Transformation

  Hong XU, Ke Di CHENG, Wei Shuo FANG, Ping ZHU, Chao MENG

  中国化学快报. 1997, 8(12): 1055-1056.

  摘要 ( ) 可视化 收藏

  A new taxoid taxa-4(20),11-diene-2α,5α,10β,14β-tetraol-2α,14β-diacetate (sinenxan H) (1) was obtained by biotransformation of taxa-4(20),11-diene-2α,5α,10β,14β-tetraol-2α,5α,10β,14β-tetraacetate (2) with a fungus isolated from Taxus yunnanensis.Its structure was determined based on spectral data.
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  A New Taxoid from the Needles of Taxus×media Hicksii

  Yong Li GAO, Jin Yun ZHOU, Yi Ding, Qi Cheng FANG

  中国化学快报. 1997, 8(12): 1057-1058.

  摘要 ( ) 可视化 收藏

  A new taxoid with 5/7/6 taxane skeleton,named taxamedin A (1) was isolated from the needles of Taxus×media Hicksii.Its structure was elucidated by spectral analysis.
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  Artselenin, a New Guaianolide from Artemisia selengensis

  Jin Feng HU, Xiao Zhang FENG

  中国化学快报. 1997, 8(12): 1059-1060.

  摘要 ( ) 可视化 收藏

  Artselenin,a new guaianolide isolated from Artemisia selengensis and its structure determination by spectral data are reported.
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  Two New Diterpenoids from Isodon Lungshengensis

  Bei JIANG, Xing Rong CHEN, Ze Qin LU, Zhong Wen LIN, Han Dong SUN

  中国化学快报. 1997, 8(12): 1061-1062.

  摘要 ( ) 可视化 收藏

  Two new diterpenoids,lungshengenin B and C (1-2),were isolated from Isodon lungshengensis.The structures were determined as 1α-hydroxy-2β,3β,11β,15β-tetraacetoxy-ent-kaur-16-en-6-one;11α-hydroxy-2β,3β,6α-triacetoxy-ent-kaur-16-en-15-one by 1D and 2D NMR techniques (COSY,HETCOR,COLOC).
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  Use of Magic Angle Spinning ¹H NMR Spectroscopy to Monitor Reactions in Solid-Phase Synthesis

  Ai Ming YU, Hua Zheng YANG, Ping Chuan SUN, Zhen Pu ZHANG, Ming LI

  中国化学快报. 1997, 8(12): 1063-1064.

  摘要 ( ) 可视化 收藏

  Proton NMR-spectra of Wang resin bound compounds were obtained using the magic angle spinning ¹HNMR technique with standard equipment.It was possible to analyse the spectra to evaluate their utility in solid-phase chemistry.A typical example was presented,which could directly monitor solid-phase reactions.
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  Determination of Vitamin D₂ and Vitamin D₃ in the Caltrate Weikang Capsules by HPLC

  Qing Tao PENG, Wen Xiang HU, Sheng Jian TAN, Pei Rang CHEN, Xiang Xian ZHANG

  中国化学快报. 1997, 8(12): 1065-1068.

  摘要 ( ) 可视化 收藏

  The Caltrate Weikang capsules made by us is a high potency calcium preparation,in which vitamin D can promote the body's calcium absorption and the bones calcification.A sensitive HPLC method for the determination of VD₂ and VD₃ in Caltrate Weikang capsules was established and VD stability was also examined.
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  Synthesis of 1-(4-Antipyrinyl)-3-(3-Chlorophenyl)-Triazene and Its Colour Reaction with Mercury

  Zhi Gang SHE, Chu Ru GoNG, Yi LUO, Ming Hua YANG

  中国化学快报. 1997, 8(12): 1069-1070.

  摘要 ( ) 可视化 收藏

  A new diazoamino reagent 1-(4-antipyrinyl)-3-(3-Chlorophenyl)-triazene(APCPT) was synthesized.The colour reaction of APCPT with Hg(Ⅱ) was studied.At pH=10.5~12.2,in the presence of Tween-80,APCPT reacts with Hg(Ⅱ) to form a red complex with high sensitivity.The molar ratio of Hg(Ⅱ) to APCPT is 1:2.The molar absorptivity is 1.87×10⁵L·mol^-1·cm^-1.Beer's law is obeyed for Hg in the range of 0-16μg/25ml.
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  The Electrochemical Impedance Behavior of the Living Cells Escherichia Coli

  Wei LI, Jun FENG, Hua Quan YANG, Yun Xiang CI

  中国化学快报. 1997, 8(12): 1071-1072.

  摘要 ( ) 可视化 收藏

  The semiconductive characteristics of electron-transferring proteins in living cells E.coli was investigated by electrochemical impedance spectroscopy (EIS).We found that the electrochemical impedance of living cells as a function of temperature followed the Arrhenius equation for semiconductors.This result shows a strong evidence to prove the semiconductive behavior of proteins.
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  Ab initio Study on the Interaction of La (Ⅲ) with Adrenaline

  Zhi Jian WU, Qing Bo MENG, Feng GAO, Chun Ji NIU, Si Yuan ZRANG

  中国化学快报. 1997, 8(12): 1073-1074.

  摘要 ( ) 可视化 收藏

  The interaction of La(Ⅲ) with adrenaline was studied using Ab initio method.The geometry of the complex of La (Ⅲ) with adrenaline was optimized,and the La(Ⅲ) bonding site in adrenaline was ascertained.