Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

doi:10.1016/j.cclet.2025.112099

中国化学快报 ›› 2026, Vol. 37 ›› Issue (02) : 112099. DOI: 10.1016/j.cclet.2025.112099

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Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

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Unraveling metabolic complexity of multi-payload PEG-irinotecan prodrug: A deconvolution-based LC-Q-TOF MS approach for preclinical pharmacokinetic characterization

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{{article.zuoZheCn_L}}. {{article.title_cn}}. {{journal.qiKanMingCheng_CN}}. 2026, 37(02): 112099 https://doi.org/10.1016/j.cclet.2025.112099

{{article.zuoZheEn_L}}. {{article.title_en}}. {{journal.qiKanMingCheng_EN}}. 2026, 37(02): 112099 https://doi.org/10.1016/j.cclet.2025.112099

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Received	Revised	Accepted	Published
2025-07-11	2025-11-10	2025-11-11	2026-02-22
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2026-02-02

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