Discovery of 3-trifluoromethyl-substituted pyrazoles as selective phosphodiesterase 10A inhibitors for orally attenuating isoprenaline-induced cardiac hypertrophy

Han Yuan, Fengcai Zhang, Hongzhe Huang, Jiafei Wu, Yi Yang, Wanyi Huang, Dongjing Yang, Zhuoming Li, Zhe Li, Ling Huang, Yi-You Huang, Hai-Bin Luo, Lei Guo

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中国化学快报 ›› 2025, Vol. 36 ›› Issue (04) : 109965. DOI: 10.1016/j.cclet.2024.109965
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Discovery of 3-trifluoromethyl-substituted pyrazoles as selective phosphodiesterase 10A inhibitors for orally attenuating isoprenaline-induced cardiac hypertrophy

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Discovery of 3-trifluoromethyl-substituted pyrazoles as selective phosphodiesterase 10A inhibitors for orally attenuating isoprenaline-induced cardiac hypertrophy

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{{article.zuoZheCn_L}}. {{article.title_cn}}. {{journal.qiKanMingCheng_CN}}. 2025, 36(04): 109965 https://doi.org/10.1016/j.cclet.2024.109965
{{article.zuoZheEn_L}}. {{article.title_en}}. {{journal.qiKanMingCheng_EN}}. 2025, 36(04): 109965 https://doi.org/10.1016/j.cclet.2024.109965

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