Email Alert
Impact Factor: 3.839
Office Online
Submission or Tracking
Peer Review
Final Decision
Editorial Center
Most Cited Articles More...
Online First Current Issue Archive Most Downloaded Most Read
Chinese Chemical Letters   2019 30( 10)  Published: 22 October 2019
Heteroatom-substituted rhodamine dyes: Structure and spectroscopic properties
Fei Deng, Zhaochao Xu
Chinese Chemical Letters 2019 Vol. 30 (10): 1667-1681   DOI:10.1016/j.cclet.2018.12.012
Abstract |  PDF (4186 KB)  ( 279 ) | HTML ( )
This review summarized the structures and photophysical properties of heteroatom-substituted rhodamines.
Synthesis and application of near-infrared substituted rhodamines
Min Li, Yuntao Li, Xijing Wang, Xiaoyan Cui, Ting Wang
Chinese Chemical Letters 2019 Vol. 30 (10): 1682-1688   DOI:10.1016/j.cclet.2019.06.036
Abstract |  PDF (937 KB)  ( 195 ) | HTML ( )
Photodynamic therapy based on organic small molecular fluorescent dyes
Li Li, Yisha Chen, Weijie Chen, Ying Tan, Haiyan Chen, Jun Yin
Chinese Chemical Letters 2019 Vol. 30 (10): 1689-1703   DOI:10.1016/j.cclet.2019.04.017
Abstract |  PDF (1463 KB)  ( 218 ) | HTML ( )
This review aims to provide a summary of the progress in organic small molecular fluorescent dyes for photodynamic therapy in recent years and it is classified according to the structures of dyes including cyanines, phthalocyanine, BODIPYs and other agents.
Small molecule fluorescent probes of protein vicinal dithiols
Guodong Hu, Huiyi Jia, Lanning Zhao, Dong-Hyung Cho, Jianguo Fang
Chinese Chemical Letters 2019 Vol. 30 (10): 1704-1716   DOI:10.1016/j.cclet.2019.06.039
Abstract |  PDF (1326 KB)  ( 118 ) | HTML ( )
Small molecule fluorescent probes that recognize and label protein vicinal dithiols have been summarized according to their different acceptor sites. This review will provide the purposeful design strategy of novel probes for detecting vicinal dithiols.
Thermally activated delayed fluorescence molecules and their new applications aside from OLEDs
Wenlong Chen, Fengling Song
Chinese Chemical Letters 2019 Vol. 30 (10): 1717-1730   DOI:10.1016/j.cclet.2019.08.032
Abstract |  PDF (1924 KB)  ( 136 ) | HTML ( )
Thermally activated delayed fluorescence molecules (TADF) molecules have been found to undergo efficient intersystem crossing (ISC) and reverse intersystem crossing (RISC) processes, which benefit their successful applications in organic light emitting diodes (OLEDs). Due to their long-lived delayed fluorescence, TADF molecules can also be applied in time-resolved luminescence imaging. Besides their special singlet properties, their excited triplet characteristics provide their potential applications in triplet-triplet annihilation upconversion (TTA-UC), photodynamic therapy (PDT) and organic photocatalytic synthesis by used as a triplet photosensitizer.
Recent advances on small-molecule fluorophores with emission beyond 1000 nm for better molecular imaging in vivo
Le Tu, Yuling Xu, Qingying Ouyang, Xiangyang Li, Yao Sun
Chinese Chemical Letters 2019 Vol. 30 (10): 1731-1737   DOI:10.1016/j.cclet.2019.05.022
Abstract |  PDF (1011 KB)  ( 132 ) | HTML ( )
Small-molecule NIR-II fluorophores play prominent roles in NIR-II biomedical research due to their promising properties such as high biocompatibility, fast excretion, favorable pharmacokinetics as well as easy and robust preparation. In order to promote the future translational practice, it is essential to design and synthesize highperformance NIR-II fluorophores.
Recent progress in two-photon small molecule fluorescent probes for enzymes
Ding Chen, Wenjing Qin, Haixiao Fang, Lan Wang, Bo Peng, Lin Li, Wei Huang
Chinese Chemical Letters 2019 Vol. 30 (10): 1738-1744   DOI:10.1016/j.cclet.2019.08.001
Abstract |  PDF (1113 KB)  ( 112 ) | HTML ( )
This review aims to provide a summary of the progress in TP small molecule fluorescent probes for enzymes in recent years and displays the main fluorescent mechanisms that have been applied to design probes.
Recent advances in the development of polydiacetylene-based biosensors
Zhijie Zhang, Fang Wang, Xiaoqiang Chen
Chinese Chemical Letters 2019 Vol. 30 (10): 1745-1757   DOI:10.1016/j.cclet.2019.08.035
Abstract |  PDF (2283 KB)  ( 104 ) | HTML ( )
The review summarizes efforts made in the development of polydiacetylene based biosensors for assaying enzyme activities, targeting tumors, imaging cells, monitoring cellular activities, and detecting microorganisms and biomolecules.
Pillararene-based fluorescent sensors for the tracking of organic compounds
Derong Cao, Herbert Meier
Chinese Chemical Letters 2019 Vol. 30 (10): 1758-1766   DOI:10.1016/j.cclet.2019.06.026
Abstract |  PDF (1321 KB)  ( 102 ) | HTML ( )
Pillararenes form versatile receptors and an alteration of the fluorescence behavior upon complexation ensures the reporter function of these chemosensors.
Our expedition in the construction of fluorescent supramolecular metallacycles
Junlong Zhu, Xi Liu, Junhai Huang, Lin Xu
Chinese Chemical Letters 2019 Vol. 30 (10): 1767-1774   DOI:10.1016/j.cclet.2019.08.027
Abstract |  PDF (1491 KB)  ( 116 ) | HTML ( )
This review summarized our efforts in the development of fluorescent supramolecular metallacycles.
Recent advances in molecular fluorescent probes for organic phosphate biomolecules recognition
Wei Li, Xiangyang Gong, Xiaopeng Fan, Shulu Yin, Dongdong Su, Xiaobing Zhang, Lin Yuan
Chinese Chemical Letters 2019 Vol. 30 (10): 1775-1790   DOI:10.1016/j.cclet.2019.07.056
Abstract |  PDF (2031 KB)  ( 124 ) | HTML ( )
This review provided a systematic overview of the recent researches on the small-molecule fluorescent probes for recognition various organic phosphate biomolecules (OPBs) including nucleotides, NAD(P)H, FAD/FMN and PS. The general strategies and the recognition mechanisms for these OPBs probe designs were described and emphasized to inspire the better design for fluorescent probes in the future.
Fluorescent probes for detection of biothiols based on “aromatic nucleophilic substitution-rearrangement” mechanism
Yan-Fei Kang, Li-Ya Niu, Qing-Zheng Yang
Chinese Chemical Letters 2019 Vol. 30 (10): 1791-1798   DOI:10.1016/j.cclet.2019.08.013
Abstract |  PDF (1120 KB)  ( 122 ) | HTML ( )
“Aromatic nucleophilic substitution-rearrangement (SNAr-rearrangement)” mechanism provided a powerful tool to design fluorescent probes for the discrimination between biothiols.
New trends of molecular probes based on the fluorophore 4-amino-1,8-naphthalimide
Lin Zhou, Lijuan Xie, Chuanhao Liu, Yi Xiao
Chinese Chemical Letters 2019 Vol. 30 (10): 1799-1808   DOI:10.1016/j.cclet.2019.07.051
Abstract |  PDF (1881 KB)  ( 97 ) | HTML ( )
4-Amino-1,8-naphthalimide (ANI) is one of the popular fluorophores for the constructions of various probes. In this review, the major progresses of ANI probes in the past decade have been highlighted and categorized into three trends. The future development of ANI probes has been expected, too.
Recent progress on pure organic room temperature phosphorescence materials based on host-guest interactions
Guojuan Qu, Yaopeng Zhang, Xiang Ma
Chinese Chemical Letters 2019 Vol. 30 (10): 1809-1814   DOI:10.1016/j.cclet.2019.07.042
Abstract |  PDF (1027 KB)  ( 87 ) | HTML ( )
The inclusion of specific organic phosphorescent guest molecules by the host molecules can reduce the nonradiative transitions and engender room temperature phosphorescence emission.
Structural modification of BODIPY: Improve its applicability
Mengdi Liu, Siyue Ma, Mengyao She, Jiao Chen, Zhaohui Wang, Ping Liu, Shengyong Zhang, Jianli Li
Chinese Chemical Letters 2019 Vol. 30 (10): 1815-1824   DOI:10.1016/j.cclet.2019.08.028
Abstract |  PDF (1833 KB)  ( 95 ) | HTML ( )
The synthesis of biocompatibility and tissue penetrating BODIPY dyes have been summarized.
Toward the most versatile fluorophore: Direct functionalization of BODIPY dyes via regioselective C—H bond activation
Wanle Sheng, Fan Lv, Bing Tang, Erhong Hao, Lijuan Jiao
Chinese Chemical Letters 2019 Vol. 30 (10): 1825-1833   DOI:10.1016/j.cclet.2019.08.004
Abstract |  PDF (1537 KB)  ( 83 ) | HTML ( )
BODIPY dyes are privileged fluorophores that are now widely used in highly diverse research fields. An overview of BODIPY dyes and a summarization of the different synthetic methodologies reported for direct C-H functionalization of the BODIPY framework have been provided.
Organelle targetable fluorescent probes for hydrogen peroxide
Ying Wen, Fangjun Huo, Caixia Yin
Chinese Chemical Letters 2019 Vol. 30 (10): 1834-1842   DOI:10.1016/j.cclet.2019.07.006
Abstract |  PDF (1322 KB)  ( 118 ) | HTML ( )
The review summarized organelle target strategies, structures, fluorescence behavior and biological applications of H2O2 fluorescent probes with mitochondria, nuclei and lysosomes-targetable ability.
Nanocrystals for large Stokes shift-based optosensing
Ronghui Zhou, Xiaomei Lu, Qin Yang, Peng Wu
Chinese Chemical Letters 2019 Vol. 30 (10): 1843-1848   DOI:10.1016/j.cclet.2019.07.062
Abstract |  PDF (1017 KB)  ( 111 ) | HTML ( )
The influence of Stokes shift in optosensing was discussed. Then, the current status of large Stokes shift-based optosensing was reviewed here.
Molecularly near-infrared fluorescent theranostics for in vivo tracking tumor-specific chemotherapy
Chenxu Yan, Limin Shi, Zhiqian Guo, Weihong Zhu
Chinese Chemical Letters 2019 Vol. 30 (10): 1849-1855   DOI:10.1016/j.cclet.2019.08.038
Abstract |  PDF (1110 KB)  ( 91 ) | HTML ( )
In this review, we summary the design concepts and strategies of NIR fluorescent theranostics for the senserelease in living systems. In particular, molecularly NIR fluorescent theranostic prodrug is elucidated to address current challenges of real-time bioimaging and tumor-specific chemotherapy for personalized treatment.
Near-infrared dyes, nanomaterials and proteins
Zong Chang, Feng Liu, Liang Wang, Mengying Deng, Chunhua Zhou, Qinchao Sun, Jun Chu
Chinese Chemical Letters 2019 Vol. 30 (10): 1856-1882   DOI:10.1016/j.cclet.2019.08.034
Abstract |  PDF (3258 KB)  ( 182 ) | HTML ( )
Near-infrared probes including dyes, nanoparticles and proteins have been particularly useful for in vivo imaging because of their ability to penetrate tissue deeper with minimal scattering and autofluorescence, opening the door to study cell biology in physiological conditions.
Copyright © 2015 Editorial Office of Chinese Chemical Letters
Address: 1 Xian Nong Tan Street, Xicheng District, Beijing, China
Zip code: 100050 Tel: 86-10-63165638 Email: