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| The application of sulfur-containing peptides in drug discovery |
| Jiaoyan Zhaoa, Xuefeng Jianga,b |
a Shanghai Key Laboratory of Green Chemistry and Chemical Process, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200062, China;
b State Key Laboratory of Elemento-organic Chemistry, Nankai University, Tianjin 300071, China |
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| Guide The purpose of the present review is to focus on the discovery of various sulfur-containing peptides with particular emphasis on their pharmacological mechanisms. This presentation is organized according to the structures of the sulfur-containing peptides. |
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Abstract In recent decades, peptides as potential drugs were more and more explored with the development of non-oral medicine. There into, sulfur-containing peptide is one of the most popular aspects in peptide drugs due to the introduction of sulfur atoms leading unique properties. The purpose of the present review is to focus on the discovery of various sulfur-containing peptides with particular emphasis on their pharmacological mechanisms. This review is organized according to the structures of the sulfurcontaining peptides.
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Received: 22 April 2018
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| Fund:The authors are grateful for financial support provided by The National Key Research and Development Program of China (No. 2017YFD0200500), the National Natural Science Foundation of China (Nos. 21722202, 21672069, 21472050), S&TCSM of Shanghai (No. 18JC1415600), S&TCSMofShanghai(No.18JC1415600),FokYingTung Education Foundation (No. 141011), DFMEC (No. 20130076110023), Professor of Special Appointment (Eastern Scholar) at Shanghai Institutions of Higher Learning, and National Program for Support of Top-Notch Young Professionals. |
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Corresponding Authors:
Xuefeng Jiang, xfjiang@chem.ecnu.edu.cn
E-mail: xfjiang@chem.ecnu.edu.cn
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