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| A minor arcutine-type C20-diterpenoid alkaloid iminium constituent of “fu zi” |
| Xian-Hua Meng, Zhi-Bo Jiang, Qing-Lan Guo, Jian-Gong Shi |
| State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, 100050, China |
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Abstract A rare arcutine-type C20-diterpenoid alkaloid, named aconicarmicharcutinium A and obtained as hydroxide (1) and trifluoroacetate (1a), was characterized as a minor constituent of "fu zi" (the lateral roots of Aconitum carmichaelii). The structures of 1 and 1a were elucidated by comprehensive analysis of spectroscopic data including 19F and 2D NMR experiments. Compounds 1 and 1a represent the first examples of the arcutine-type C20-diterpenoid alkaloid iminium.
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Received: 02 September 2016
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| Fund:Financial support from the National Natural Science Foundation of China (NNSFC; Nos. 81630094 and 30825044) is acknowledged. |
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Corresponding Authors:
Jian-Gong Shi
E-mail: shijg@imm.ac.cn
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