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A new cerebroside and its anti-proliferation effect on VSMCs from the radix of Cyperus rotundus L. |
Pei Liu, Li Liu, Yu Ping Tang, Jin Ao Duan, Nian Yun Yang |
Jiangsu Key Laboratory for TCM Formulae Research, Nanjing University of Chinese Medicine, Nanjing 210046, China |
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Abstract A new cerebroside, 1-O-(β-D-glucopyranosyloxy)-(2S,3R,4E,8Z)-2- [(2'R)-2'-hydroxylignoceranoylainino]-4,8-tetradecene-3-diol was isolated from the 60% EtOH extract of traditional Chinese medical plant Cyperus rotundus L. Its structure was determined on the basis of spectroscopic data. This new compound showed anti-proliferation effect on vascular smooth muscle cells (VSMCs).
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Received: 22 September 2009
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Fund:This research was supported by 2006 Great Basic Science Research Project of Jiangsu College and University (No. 06KJA36022). We also thank Dr. Dong Jun Chen, Dr. Er Xin Shang, Dr. Jun Sun, Dr. Shu Lan Su and Bin Bin Huang for other helpful assistance. |
Corresponding Authors:
Jin Ao Duan,E-mail address:dja@njutcm.edu.cn
E-mail: dja@njutcm.edu.cn
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