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| Three new phenanthrenes from Monomeria barbata Lindl. |
| Ming Hui Yanga,b, Le Caia, Mei Hong Lia, Xiang Hui Zenga, Ya Bin Yanga, Zhong Tao Dinga |
a Key Laboratory of Medicinal Chemistry for Nature Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming 650091, China;
b Department of Biochemistry, Dali College, Dali 671000, China |
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Abstract Three new monophenanthrene compounds were isolated from an acetone extract of the tubers of Monomeria barbata Lindl. (Orchidaceae). Using spectroscopic methods, the structures of compounds 1-3 were determined as 1,4,7-trihydroxy-2-methoxy-9,10-dihydrophenanthrene (1), 1-(p-hydroxybenzoyl)-2-methoxy-4,7-dihydroxy-9,10-dihydrophenunthrene (2), 1,3,8-tri(p-hydroxybenzyl)-4-methoxy-phenanthrene-4,7-diol (3). These compounds showed cytotoxicities on four tumor cell lines (HepG2, HL-60, Skov-3, A431).
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Received: 26 June 2009
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| Fund:This work was supported by a program for New Century Excellent talents in University from MOE (NCET-08-0925), a grant from the Natural Science Foundation of Yunnan Province (No. 2007B021M) and a grant from Yunnan University (No. 2007Q003A). |
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Corresponding Authors:
Zhong Tao Ding,E-mail address:ztding@ynu.edu.cn
E-mail: ztding@ynu.edu.cn
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