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A clean and efficient cyclocondensation to pyrido[2,3-d]pyrimidine derivatives in aqueous media |
Robabeh Baharfar, Razieh Azimi |
Faculty of Chemistry, Mazandaran University, Babolsar, Iran |
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Abstract A series of pyrido[2, 3-d]pyrimidine derivatives were easily constructed by cyclocondensation reactions of 6-aminouracils or 6-aminothiouracil with α, β-unsaturated carbonyl compounds (aldehyde, ketone and ester) possessing a leaving group on the β position, in H2O under reflux conditions.
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Received: 17 February 2011
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Fund:Financial support of this work from the Research Council of Mazandran University is gratefully acknowledged. |
Corresponding Authors:
Robabeh Baharfar,E-mail address:baharfar@umz.ac.ir
E-mail: baharfar@umz.ac.ir
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About author:: 10.1016/j.cclet.2011.04.020 |
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