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| Synthesis of 2,3-dihydroquinazolin-4(1H)-ones catalyzed by zirconium (IV) chloride as a mild and efficient catalyst |
| Mohammad Abdollahi-Alibeik, Elahe Shabani |
| Department of Chemistry, Yazd University, Yazd 89195-741, Iran |
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Abstract 2, 3-Dihydroquinazolin-4 (1H)-ones have been synthesized in the high to excellent yields via condensation of 2-aminobenzamide with aldehydes and ketones in the presence of catalytic amount of ZrCl4 in EtOH at room temperature. Mild reaction conditions, clean reaction media, simple workup and easy purification are advantages of this methodology.
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Received: 05 January 2011
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| Fund:We are thankful to the Yazd University Research Council for partial support of this work. |
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Corresponding Authors:
Mohammad Abdollahi-Alibeik,E-mail address:abdollahi@yazduni.ac.ir
E-mail: abdollahi@yazduni.ac.ir
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| About author:: 10.1016/j.cclet.2011.05.011 |
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Ming-Hua Chen, Sheng Lin, Ya-Nan Wang, Cheng-Gen Zhu, Yu-Huan Li, Jian-Dong Jiang, Jian-Gong Shi. Antiviral stereoisomers of 3,5-bis(2-hydroxybut-3-en-1-yl)-1,2, 4-thiadiazole from the roots of Isatis indigotica[J]. CCL, 2016, 27(05): 643-648. |
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