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| Microwave assisted, ligand free, copper catalyzed reaction of aryl halides with phenyl urea |
| Sandip N. Gavadea, Ravi S. Balaskara, Madhav S. Manea, Pramod N. Pabrekarc, Murlidhar S. Shingareb, Dhananjay V. Manea |
a Organic Research Laboratory, S.C.S. College, Omerga 413 606 (MS), India;
b Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431 004 (MS), India;
c V.G. Vaze College, Mulund(E), Mumbai 400081 (MS), India |
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Abstract The ligand free coupling reaction of phenyl urea with different functionalized aryl halides in the presence of air stable Cu2O and t-BuOK as a base gives symmetrical and unsymmetrical diarylureas in relatively high yields. This method is milder than the palladium catalyzed arylation and avoids the use of toxic phosphine ligand.
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Received: 17 June 2010
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| Fund:Authors are thankful to Head of Department of Chemistry V.G. Vaze College, Mulund (E), Mumbai-81(MS), India for providing the necessary laboratory facilities. |
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Corresponding Authors:
Dhananjay V. Mane,E-mail address:dr_dvmane@rediffmail.com
E-mail: dr_dvmane@rediffmail.com
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