Abstract Nucleophilic aromatic substitution of hydrogen in non-activated aromatic ring, a very rare phenomenon in organic chemistry, is found in ionic liquids containing Cl-as anion under mild reaction conditions. The reaction may be carried out by the addition of the halogen-bonding adduct (Br2Cl-) as nucleophile to aromatic ring carbon atom, leading to the formation of the nucleophilic substitution product.
Received: 22 July 2010
Fund:We thank the key project of Shanghai Science and Technology Committee (Nos. 05JC14070, 06DZ05025, 08JC1408600) for financial supports.
Yong Kui Shan,E-mail address:firstname.lastname@example.org