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Synthesis and activity evaluation of some novel derivatives of 4,5,6,7-tetrahydrothieno [3,2-c]-pyridine |
Die Chenga,b, Deng Ke Liub, Mo Liub, Ying Liub, Wei Ren Xub, Chang Xiao Liub |
a Department of Pharmaceutical Engineering, School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China; b state Key Laboratory of Pharmacokinetics and Pharmacodynamics, Tianjin Institute of Pharmaceutical Research, Tianjin 300193, China |
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Abstract Two series of novel derivatives of 4,5,6,7-tetrahydromieno [3,2-c] pyridine were synthesized and structurally characterized by 1H NMR and MS. Their in vivo antiplatelet aggregation activities were evaluated.
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Received: 17 January 2008
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Corresponding Authors:
Chang Xiao Liu, E-mail address:liuchangxiao@163.com
E-mail: liuchangxiao@163.com
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About author:: 10.1016/j.cclet.2008.03.035 |
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[1] |
Die Cheng, Deng Ke Liu, Mo Liu, Ying Liu, Wei Ren Xu, Chang Xiao Liu. Synthesis, activity evaluation and 3D-QSAR study of some novel derivatives of 4, 5, 6, 7-tetrahydrothieno [3,2-c] pyridine[J]. CCL, 2008, 19(09): 1075-1079. |
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