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| Immunosuppressive terpenoids from Tripterygium wilfordii |
| Qian Shena, ZhiYaob, Yoshihisa Takaishic, Yan Wen Zhanga,b,c, Hong Quan Duana |
a School of Pharmaceutical Sciences, Basic Medical Research Center of Tianjin, Tianjin Medical University, Tianjin 300070, China;
b Department of Immunology, Tianjin Medical University, Tianjin 300070, China;
c Faculty of Pharmaceutical Sciences, University of Tokushima, Tokushima 770-8505, Japan |
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Abstract Two new terpenes, triptobenzene P (1) and wilforone (2) were isolated from Tripterygium wilfordii, as well as 10 known terpenes.Their structures were elucidated by spectroscopic methods.Compounds 2-4, 8, 10, and 11 showed significantimmunosuppressive activities.
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Received: 18 October 2007
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Corresponding Authors:
Hong Quan Duan,E-mail address:duanhq@tijmu.edu.cn
E-mail: duanhq@tijmu.edu.cn
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