Abstract A novel axially substituted silicon(IV) phthalocyanine, namely di-pyridyloxy axially substituted silicon(IV) phthalocyanine 2 was synthesized and characterized by UV/vis, IR, elemental analysis, MS as well as 1H NMR spectroscopy. Hydrophobic 2 was encapsulated by amphiphilic triblock copolymer poly[Nε-(benzyloxycarbonyl-lysine]-poly(ethylene glycol)-poly[Nε-(benzyl oxycarbonyl) (PLL(Z)-b-PEG-b-PLL(Z)) to form hydrophobic 2-loaded polymeric complex micelle (PIC) (2-loaded PIC). Atom force microscopy (AFM) image showed that 2-loaded PIC formed a spherical nanocarrier with approximately 35-50 nm in diameter. The fluorescence intensity and lifetime of 2-loaded PIC was significantly enhanced by the incorporation 2 into PIC nanocarrier.
Received: 10 September 2008
Fund:This study was supported by the National Natural Science Foundation of China (No.20604007), Natural Science Foundation of Fujian (No.2008J0078), Key Foundation for Ministry of Education, China (No.206071), Project WKJ2008-2-61 supported by science research foundation of Ministry of Health&United Fujian Provincial Health and Education Project for Tackling the Key Research, China.
Bao Quan Huang,E-mail:firstname.lastname@example.org