A new polyketide synthase nonribosomal peptide synthetase hybrid metabolite from plant endophytic fungus <em>Periconia</em> sp.

doi:10.1016/j.cclet.2016.02.005

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Abstract A new polyketide synthase-nonribosomal peptide synthetase (PKS-NRPS) hybrid metabolite, named pericoannosin B (1), was isolated from endophytic fungus Periconia sp. F-31 of the medicinal plant Annona muricata. The structure and absolute configuration were elucidated by means of extensive spectroscopic analyses (HRMS, NMR, IR, and CD).

Key words： Endophytic fungus Periconia PKS-NRPS Pericoannosin B

Received: 15 December 2015 Published: 02 March 2016

Fund:This work was financially supported by the National Natural Science Foundation of China (Nos. 31170041 and 81402835), the National High Technology Research and Development Program of China (No. 2012AA091606), and The National Infrastructure of Microbial Resources (No. NIMR-2015-3).

Corresponding Authors: Li-Yan Yu, Jun-Gui Dai E-mail: yly@cpcc.ac.cn;jgdai@imm.ac.cn

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http://www.chinchemlett.com.cn/EN/10.1016/j.cclet.2016.02.005 OR http://www.chinchemlett.com.cn/EN/Y2016/V27/I05/640

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