|
|
Two new triterpenoid saponins from notoginseng medicinal fungal substance |
Wei Xu, Cai-Feng Ding, Xin-Wen Wang, Xiao-Li Liu, Zhi-Dong Qiu |
College of Pharmacy, Changchun University of Chinese Medicine, Changchun 130117, China |
|
|
Abstract Two new triterpenoid saponins, named ginsenoside Rh10 (1) and notoginsenoside ST-6 (2), were isolated from notoginseng medicinal fungal substance. Their structures were elucidated by a combination of 1D and 2D NMR, MS and chemical analysis.
|
Received: 14 April 2015
Published: 14 July 2015
|
Fund:This project was financially supported by National Science and Technology Supporting Plan of China (No. 2012BAI29B05). |
Corresponding Authors:
Zhi-Dong Qiu
E-mail: 13321549939@163.com
|
|
|
|
[1] |
B. Chen, H.L. Xu, X.B. Jia, Research progress and thought on processing of Panax notoginseng, Chin. Tradit. Herb. Drugs 44(2013) 482-487.
|
[2] |
X.H. Wang, Q.D. Li, Q.E. Cao, New field for study of TCM through fermentation by microbe, Chin. Tradit. Herb. Drugs 32(2001) 267-268.
|
[3] |
M. Górecki, A. Kamińska, P. Ru?kowska, A. Suszczyńska, J. Frelek, Dimolybdenum method for determination of the absolute configuration of vic-diols-foundations and developments, Pol. J. Chem. 80(2006) 523-534.
|
[4] |
J. Frelek, A. Klimek, P. Ruskowska, Dinuclear transition metal complexes as auxiliary chromophores in chiroptical studies on bioactive compounds, Curr. Org. Chem. 7(2003) 1081-1104.
|
[5] |
M. Górecki, E. Jab?ońska, A. Kruszewska, et al., Practical method for the absolute configuration assignment of tert/tert 1,2-diols using their complexes with Mo2(OAc)4, J. Org. Chem. 72(2007) 2906-2916.
|
[6] |
L. Di Bari, G. Pescitelli, C. Pratelli, D. Pini, P. Salvadori, Determination of absolute configuration of acyclic 1, 2-diols with Mo2(OAc)4. 1. Snatzke's method revisited, J. Org. Chem. 66(2001) 4819-4825.
|
[7] |
M. Politi, N. De Tommasi, G. Pescitelli, et al., Structure and absolute configuration of new diterpenes from Lavandula multifida, J. Nat. Prod. 65(2002) 1742-1745.
|
[8] |
J. Liu, Y.B. Liu, Y.K. Si, et al., New vernocuminosides from the stem barks of Vernonia cumingiana Benth, Steroids 74(2009) 51-61.
|
[9] |
L.F. Han, K.J. Sakah, L.L. Liu, et al., Saponins from roots of Panax notoginseng, Chin. Herb. Med. 6(2014) 159-163.
|
[10] |
B.H. Han, M.H. Park, Y.N. Han, et al., Degradation of ginseng saponins under mild acidic conditions, Planta Med. 44(1982) 146-149.
|
[11] |
W. Xu, J.M. Wu, Z. Zhu, et al., Pentacyclic triterpenoid saponins from Silene viscidula, Helv. Chim. Acta 93(2010) 2007-2014.
|
[12] |
P.Y. Liao, D. Wang, Y.J. Zhang, C.R. Yang, Dammarane-type glycosides from steamed notoginseng, J. Agric. Food Chem. 56(2008) 1751-1756.
|
|
|
|