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| Tetraphenylethene based zinc complexes as fluorescent chemosensors for pyrophosphate sensing |
| Hao-Ran Xu, Kun Li, Shu-Yan Jiao, Ling-Ling Li, Sheng-Lin Pan, Xiao-Qi Yu |
| Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry, Sichuan University, Chengdu 610064, China |
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| Guide Three novel tetraphenylethene and nitrogen heterocycles based zinc complex were presented as novel fl uorescent ensembles for nanomolar pyrophosphate sensing in 100% aqueous solution |
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Abstract We described a serious of zinc complexes that exhibit characteristic fluorescence responses toward pyrophosphate (PPi) and adenosine triphosphate (ATP) in aqueous media. These novel probes exploited tetraphenylethene (TPE) as fluorophore and macrocycle-polyamine (including 1,4,7,10-tetraazacyclododecane and 1,4,7-triazacyclononane) Zn(II) complexes as binding group. These “OFF-ON” type probes exhibited promising selectivity and sensitivity to PPi and ATP via a restriction of intramolecular rotation (RIR) mechanism. The detection limit for PPi was found within nmol/L range.
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Received: 25 January 2015
Published: 29 May 2015
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| Fund: This work was financially supported by the National Program on Key Basic Research Project of China (973 Program, Nos. 2012CB720603, 2013CB328900), the National Science Foundation of China (Nos. 21232005, 21321061, J1310008and J1103315), and the Specialized Research Fund for the Doctoral Program of Higher Education in China (No. 20120181130006). |
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Corresponding Authors:
Kun Li, Xiao-Qi Yu
E-mail: kli@scu.edu.cn;xqyu@scu.edu.cn
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