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| A novel approach for synthesis of 3-amino-5-aryl-2,5-dihydropyridazines using onium salt as soluble support |
| Meng Gao, Cui Fen Lu Gui Chun Yang, Zu Xing Chen |
| Ministry-of-Education Key Laboratory for the Synthesis and Application of Organic Functional Molecule & School of Chemistry and Chemical Engineering, Hubei University, Wuhan 430062, China |
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Abstract In this work it was presented an application of task specific onium salt as soluble support for the synthesis of 3-amino-5-ary 1-2,5-dihydropyridazines. This soluble support is of wide applicability and combines advantages of solid phase synthesis without its limitations with those of solution phase chemistry. After a simple washing step, products were cleaved from the supports and obtained in good yields.
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Received: 29 October 2010
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| Fund:We gratefully acknowledge the Natural Sciences Foundation of Hubei province in China (Nos.2007ABA031 and 2008CDA078). |
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Corresponding Authors:
Meng Gao, E-mail address:lucf@hubu.edu.cn
E-mail: lucf@hubu.edu.cn
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