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| A highly flexible green synthesis of 1H-pyrazolo[1,2-b]phthalazine-5,10-dione derivatives with CuI nanoparticles as catalyst under solvent-free conditions |
| Javad Safaei-Ghomi, Hossein Shahbazi-Alavi, Abolfazl Ziarati, Raheleh Teymuri, Mohammad Reza Saberi |
| Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, Kashan 51167, Iran |
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Abstract CuI nanoparticles as an efficient catalyst have been used for the preparation of 1H-pyrazolo[1,2-b]phthalazine-5,10-diones by the four-component condensation reaction of phthalic anhydride, hydrazine monohydrate, aromatic aldehydes and malononitrile or ethyl cyanoacetate under solventfree conditions in good to excellent yields, short reaction times and environmentally benign, milder reaction conditions.
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Received: 13 August 2013
Published: 28 November 2013
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| Fund: The authors are grateful to University of Kashan for supporting this work (No. 159196/XⅡV). |
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Corresponding Authors:
Javad Safaei-Ghomi
E-mail: safaei@kashanu.ac.ir
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